Multivariable MR Tutorial5 months ago
Overview | Workflow | Step 1: Obtain summary data | Estimating pairwise covariances between SNP associations | Step 2: Format summary data | Step 3: Test for weak instruments | Step 4: Test for horizontal pleiotropy using conventional Q-statistic estimation | Step 5: Estimate causal effects | Step 6: Robust causal effect estimation. | References
MVMR 0.4.8Wes Spiller, Eleanor Sanderson, and Jack BowdenMVMR.rmd